Related Experiment Video
Updated: Apr 21, 2026

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures
Published on: November 2, 2015
Chronic hypoxemia in a child: thinking outside the box
Barath Jagadisan1, Sriram Krishnamurthy, Renitha Raghavan
1Departments of Pediatrics and *Radiodiagnosis, JIPMER, Pondicherry, India. Correspondence to: Dr Sriram Krishnamurthy, Associate Professor, Department of Pediatrics, JIPMER, Pondicherry 605 006, India. drsriramk@yahoo.com.
Background:
Chronic hypoxemia is generally attributed to primary cardiac or pulmonary entities.
Case Characteristics:
A 9-year-old boy presenting with cyanosis, clubbing and hypoxemia, without icterus or hepatosplenomegaly. Cardiovascular and respiratory system examinations were normal.
Outcome:
He was diagnosed as type IB Abernethy malformation, a rare cause of hepatopulmonary syndrome.
Message:
Pediatricians should consider hepatopulmonary syndrome in the differential diagnosis of chronic hypoxemia, even in the absence of jaundice or hepatosplenomegaly.
Related Concept Videos
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Hypoxia
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Physiological Control of Respiration
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History

