Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

803
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
803
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

1.7K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.7K
Hypoxia01:23

Hypoxia

2.3K
Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
2.3K
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

2.0K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
2.0K
Physiological Control of Respiration01:23

Physiological Control of Respiration

4.7K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
4.7K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.3K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microbial Conversations Between the Gut and Urinary Tract: Emerging Implications for Kidney and Urinary Tract Diseases.

Indian pediatrics·2026
Same author

A Longitudinal Study of Clinical Outcomes and Efficacy of Mycophenolate Mofetil in Pediatric Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome.

Indian pediatrics·2026
Same author

Streptococcus Pneumoniae-Associated Hemolytic Uremic Syndrome: Experience with Managing Three Pediatric Cases.

Indian pediatrics·2026
Same author

Evaluation of cardiovascular morbidities in children and adolescents with lupus nephritis from south India: A cross-sectional analytical study.

Lupus·2026
Same author

Refractory Rickets: Evaluation and Management.

Indian journal of pediatrics·2026
Same author

Reference Change Value Based AKI Criteria in Critically Ill Children.

Kidney international reports·2026

Related Experiment Video

Updated: Apr 21, 2026

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures
05:45

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures

Published on: November 2, 2015

6.7K

Chronic hypoxemia in a child: thinking outside the box.

Barath Jagadisan1, Sriram Krishnamurthy, Renitha Raghavan

  • 1Departments of Pediatrics and *Radiodiagnosis, JIPMER, Pondicherry, India. Correspondence to: Dr Sriram Krishnamurthy, Associate Professor, Department of Pediatrics, JIPMER, Pondicherry 605 006, India. drsriramk@yahoo.com.

Indian Pediatrics
|November 2, 2014
PubMed
Summary

This study highlights a rare cause of chronic hypoxemia in children: Abernethy malformation. Pediatricians should consider hepatopulmonary syndrome in diagnosing hypoxemia, even without typical jaundice symptoms.

More Related Videos

A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

8.5K
A Swine Model of Neonatal Asphyxia
10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

14.0K

Related Experiment Videos

Last Updated: Apr 21, 2026

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures
05:45

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures

Published on: November 2, 2015

6.7K
A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

8.5K
A Swine Model of Neonatal Asphyxia
10:36

A Swine Model of Neonatal Asphyxia

Published on: October 11, 2011

14.0K

Area of Science:

  • Pediatric Gastroenterology
  • Pulmonology
  • Medical Diagnostics

Background:

  • Chronic hypoxemia is typically linked to cardiac or pulmonary conditions.
  • Investigating rare etiologies is crucial for comprehensive diagnosis.

Observation:

  • A 9-year-old boy presented with cyanosis, clubbing, and hypoxemia.
  • Physical examination revealed normal cardiovascular and respiratory systems, with no jaundice or hepatosplenomegaly.

Findings:

  • The patient was diagnosed with type IB Abernethy malformation.
  • This rare congenital anomaly was identified as the cause of hepatopulmonary syndrome.

Implications:

  • Hepatopulmonary syndrome should be considered in the differential diagnosis of pediatric chronic hypoxemia.
  • Clinicians must consider rare conditions like Abernethy malformation, even with atypical presentations.