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Published on: May 16, 2025
Drug therapies for peripheral joint disease in psoriatic arthritis: a systematic review
Maria Laura Acosta Felquer1, Laura C Coates1, Enrique R Soriano1
1From the Sección Reumatología, Servicio de Clínica Médica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Sección Reumatología, Servicio de Clínica Médica, Hospital Italiano de Buenos Aires; Academic Unit of Rheumatology, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil; Section of Rheumatology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA; Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital, Leeds, UK; Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College, Dublin, Ireland; Department of Pharmacy and Pharmacology, University of Bath, Bath, UK; Barking Havering and Redbridge University Hospitals, NHS Trust; and Queens Mary's University of London, London, UK; and Swedish Medical Center, University of Washington School of Medicine, Seattle, Washington, USA.M.L. Acosta Felquer, MD, Sección Reumatología, Servicio de Clínica Médica, Hospital Italiano de Buenos Aires; L.C. Coates, MRCP, PhD, NIHR Clinical Lecturer, Leeds Institute; E.R. Soriano, MD, MSC, Jefe Sección Reumatología, Servicio de Clínica Médica, Hospital Italiano de Buenos Aires; R. Ranza, MD, Academic Unit of Rheumatology, Universidade Federal de Uberlândia; L.R. Espinoza, MD, Section of Rheumatology, Louisiana State University Health Sciences Center; P.S. Helliwell, DM, PhD, Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital; O. FitzGerald, MD, Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College; N. McHugh, FRCP, MD, Department of Pharmacy and Pharmacology, University of Bath; E. Roussou, MD, Consultant Rheumatologist, Barking Havering and Redbridge University Hospitals, NHS Trust and Clinical Senior Lecturer, Queens Mary's University of London; P.J. Mease, MD, Rhe
Abstract:
In 2009, GRAPPA published their first evidence-based recommendations for the treatment of psoriasis and psoriatic arthritis (PsA). Since then, new information has been published and drugs developed. We summarize evidence for the efficacy of available treatments for peripheral joint involvement in PsA. We performed a systematic review of current literature on the efficacy of different therapies, management, and therapeutic strategies for peripheral arthritis involvement in PsA, in order to provide information for the development of the new GRAPPA treatment recommendations.

