Related Experiment Video

Updated: Apr 21, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

23.9K

Case report: Diaper dermatitis presenting as pustules

Ann T Tucker, Ashley N Emerson, Julie P Wyatt

    Journal of Drugs in Dermatology : JDD
    |November 4, 2014
    PubMed

    Insights

    Diaper dermatitis, common in infants, is often diagnosed by its appearance. Distinguishing between irritant and fungal causes, like Candida, is key for effective treatment.

    Area of Science:

    • Pediatric Dermatology
    • Infant Health
    • Dermatologic Disorders

    Background:

    • Diaper dermatitis represents the most frequent dermatologic condition observed in infants.
    • Clinical presentation is often sufficient for determining the cause of diaper dermatitis.

    Observation:

    • Primary diaper dermatitis, linked to irritants, typically spares the deeper skin folds.
    • Secondary diaper dermatitis often results from Candida yeast overgrowth, presenting with erythema in folds and satellite pustules.

    Findings:

    • Differentiating between irritant and fungal diaper dermatitis is crucial for appropriate management.
    • A potassium hydroxide (KOH) preparation can confirm Candida infections.

    Implications:

    • Accurate clinical diagnosis and simple diagnostic tests guide effective treatment strategies for infant diaper dermatitis.
    • Understanding the etiology of diaper dermatitis ensures targeted therapies, improving infant skin health.

    More Related Videos

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis07:22

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

    Published on: March 14, 2025

    1.4K
    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus05:39

    Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

    Published on: May 16, 2025

    919

    Related Concept Videos

    Acne Infection01:27

    Acne Infection

    Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
    81
    Accessory Structures of the Skin: Sebaceous Glands01:21

    Accessory Structures of the Skin: Sebaceous Glands

    A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
    These glands that produce the oils on the skin and hair are holocrine glands. The mature...
    5.4K
    Skin Diseases and Disorders01:23

    Skin Diseases and Disorders

    Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
    Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
    5.1K
    Staphylococcal Skin Infections01:29

    Staphylococcal Skin Infections

    Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
    121
    Papillary Dermis01:11

    Papillary Dermis

    Dermis
    The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
    Papillary Layer
    The papillary layer is made of loose, areolar connective tissue, which means the collagen...
    5.7K
    The Skin Microbiota01:27

    The Skin Microbiota

    The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
    103