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Influx of patients with asthma-like symptoms strains resources in many pediatric EDs
Insights
A rare enterovirus D68 (EV-D68) outbreak is causing a surge in pediatric emergency department visits nationwide. Many children present with asthma-like symptoms, and some cases involve neurological issues.
Area of Science:
- Public Health
- Virology
- Pediatrics
Background:
- An enterovirus D68 (EV-D68) outbreak has emerged in the United States, affecting at least 40 states.
- Pediatric emergency departments (EDs) are experiencing significant patient volume increases due to the outbreak.
- Children typically present with asthma-like symptoms, raising concerns for respiratory distress.
Purpose of the Study:
- To report on the emergence and impact of the EV-D68 outbreak on pediatric EDs.
- To highlight the clinical presentation of EV-D68 in children.
- To alert healthcare providers about the escalating patient volumes and potential for patient surges.
Main Methods:
- Surveillance of reported EV-D68 cases across multiple states.
- Monitoring of patient volumes and clinical presentations in pediatric EDs.
- Investigation into potential links between EV-D68 and neurological symptoms in pediatric patients.
Main Results:
- EV-D68 cases confirmed in at least 40 states, originating in the Midwest.
- Significant increases in patient volume observed in pediatric EDs, with some hospitals reporting 40+ additional patients daily.
- A cluster of nine pediatric cases with muscle weakness or paralysis in Colorado and Massachusetts is under investigation for a potential link to EV-D68.
Conclusions:
- The EV-D68 outbreak necessitates preparedness for sustained patient surges in pediatric EDs.
- Early recognition of EV-D68 symptoms, particularly asthma-like presentations, is crucial for timely diagnosis and management.
- Further investigation is required to understand the full spectrum of EV-D68's clinical manifestations, including potential neurological complications.
Abstract:
An outbreak of a rarely seen virus in the United States is spiking volumes at pediatric EDs across the country, with children typically presenting with asthma-like symptoms. Cases of enterovirus D68 (EV-D68) first emerged in the Midwest in early August, but the virus has since been confirmed in at least 40 states. The CDC is also investigating whether a cluster of nine pediatric cases involving young patients with muscle weakness or paralysis are related to the EV-D68 outbreak. The patients are all hospitalized in Colorado and Massachusetts. Children's Mercy Hospital in Kansas City, MO, first alerted the CDC that the ED was seeing an unusual in spike in patients coming in with asthma-like symptoms. By mid-September, the hospital had seen 500 confirmed cases of EV-D68, including 60 patients who were admitted to the pediatric intensive care unit. Patient volume in the ED at the University of Chicago Medicine Comer Children's Hospital is up by about 40 patients per day, with most reporting symptoms consistent with EV-D68. Emergency department leaders from hospitals impacted by the outbreak advise colleagues to put plans in place for an extended surge of patients because patient volumes can escalate quickly.
Related Concept Videos
Asthma III: Clinical Manifestations
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Asthma I: Introduction
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-I: Introduction
Allergic Reactions

