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Published on: November 2, 2015
Respiratory inhibition after crying and feeding hypoxemia in infants
Hideki Minowa1, Kouichiro Hirayama2, Reiko Tamura1
1a Department of Neonatal Intensive Care Unit , Nara Prefecture General Medical Center , Nara , Japan and.
Insights
Respiratory inhibition after crying (RIAC) and feeding hypoxemia are common in healthy infants. These conditions involve repeated, prolonged hypoxemia, with most infants recovering but some requiring extended monitoring.
Area of Science:
- Neonatal physiology
- Pediatric cardiology
- Clinical pediatrics
Background:
- Respiratory inhibition after crying (RIAC) and feeding hypoxemia are clinical events in neonates.
- Understanding their incidence and risk factors is crucial for infant care.
Purpose of the Study:
- To determine the incidence, risk factors, and natural history of RIAC and feeding hypoxemia.
- To investigate correlations between these events and other neonatal factors.
Main Methods:
- A cohort of 393 infants with gestational age ≥36 weeks was screened using pulse oximetry.
- Twenty-seven infants required neonatal intensive care unit (NICU) treatment.
Main Results:
- RIAC occurred in 24.2% and feeding hypoxemia in 31.6% of infants.
- Both conditions correlated significantly with each other and with factors like abnormal cranial ultrasound findings, twin gestation, and maternal smoking.
- All infants recovered from RIAC; 10 infants with feeding hypoxemia required extended monitoring.
Conclusions:
- RIAC and feeding hypoxemia are observed in healthy infants.
- These conditions can lead to repeated episodes of prolonged hypoxemia.
- While most infants recover, some may need additional monitoring and support.
Objective:
To determine the incidence, risk factors and natural history of respiratory inhibition after crying (RIAC) and feeding hypoxemia.
Methods:
We screened for RIAC and feeding hypoxemia among 393 infants with a gestational age ≥ 36 weeks using pulse oximetry. Twenty-seven infants were treated in the neonatal intensive care unit.
Results:
RIAC and feeding hypoxemia were observed in 95 (24.2%) and 124 (31.6%) infants, respectively. RIAC correlated with feeding hypoxemia (p < 0.001), grade II increased echogenicity in the ganglionic eminence (p = 0.005), dilation of the lateral ventricle (p = 0.044), threatened premature labor (p = 0.033) and twin gestation (p = 0.089). Feeding hypoxemia correlated with RIAC (p < 0.001), abnormal cranial ultrasound findings (p < 0.001), maternal smoking during pregnancy (p = 0.083), asymmetric intrauterine growth restriction (p = 0.012) and twin gestation (p = 0.067). All infants recovered from RIAC in an average of 4.5 (2.0-7.0) d. Fifteen infants recovered from feeding hypoxemia, but 10 infants needed additional assistance and monitoring by nursing until the day of discharge. The day of discharge was day 8.0 (5.0-12.4).
Conclusions:
RIAC and feeding hypoxemia are observed among healthy infants, and these infants experience repeated events of prolonged hypoxemia.
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