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Related Experiment Video

Updated: Apr 21, 2026

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
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Shaving effects on percutaneous penetration: clinical implications.

Muhammad Hamza1, Hassaan Tohid2, Howard Maibach1

  • 1a Department of Dermatology , University of California San Francisco , San Francisco , USA and.

Cutaneous and Ocular Toxicology
|November 4, 2014
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Summary

Shaving can increase how much certain chemicals penetrate the skin, but this effect varies by species and chemical. More research is needed to understand the full impact of shaving on skin absorption.

Keywords:
Blade and absorptiondyes and skin permeationhair removalrazor and shaveshave and absorptionstratum corneum and axillary shaving

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Area of Science:

  • Dermatology
  • Toxicology

Background:

  • Explores the biological implications of human and animal shaving.
  • Investigates the relationship between shaving practices and skin physiology.

Purpose of the Study:

  • To evaluate how shaving influences percutaneous penetration.
  • To assess the impact of shaving on overall skin function.

Main Methods:

  • Conducted a comprehensive literature search across major databases (PubMed, Scopus, Cochrane Library).
  • Screened over 500 publications, selecting 17 relevant studies.
  • Utilized search terms related to shaving, skin penetration, absorption, and specific applications like dyes and axillary shaving.

Main Results:

  • Shaving appears to significantly enhance percutaneous absorption.
  • Evidence suggests that shaving's effect on absorption is not universally supported across all studies.

Conclusions:

  • Shaving can enhance the percutaneous penetration of certain chemicals.
  • The observed effect is specific to the species and the chemical properties involved.
  • Further research is required to generalize findings on shaving's impact on skin absorption.