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Updated: Apr 21, 2026

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Automated System for Single Molecule Fluorescence Measurements of Surface-immobilized Biomolecules
Published on: November 2, 2009
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An iminocoumarin sulfonamide based turn-on fluorescent probe for the detection of biothiols in aqueous solution
Yan-Ling Yang1, Fu-Ming Zhang, Ya-Wen Wang
1Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000 (P. R. China), Fax: (+86) 931-8912582.
Chemistry, an Asian Journal
|November 4, 2014
Abstract:
A new chemodosimeter for the highly selective sensing and imaging of biothiols was designed and realized in phosphate-buffered saline solution at pH 7.4 through a fluorescence "off-on" response. A unique mechanism featuring a two-step cascade (biothiols→H2 O) sequence for this remarkable recognition is disclosed for the first time.

