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Updated: Apr 21, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

Telangiectatic osteosarcoma affecting the mandible.

Lr Kumaraswamy Naik¹, Pushparaja Shetty², S Teerthanath³

¹Department of Oral Pathology and Microbiology, Sri Jagadguru Murugharajendra Dental College and Hospital, Chitradurga, Karnataka, India.

Journal of Oral and Maxillofacial Pathology : JOMFP

|November 4, 2014

Summary

This study reports the first pediatric case of telangiectatic osteosarcoma in the mandible. The patient achieved a seven-year disease-free survival after hemimandibulectomy, highlighting successful treatment for this rare jaw cancer.

Keywords:

Aneurysmal bone cyst mandible paediatric patient telangiectatic osteosarcoma

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Area of Science:

Oncology
Pediatric Oncology
Oral and Maxillofacial Surgery

Background:

Osteosarcomas of the jaw are rare, particularly in pediatric patients.
Telangiectatic osteosarcoma is an exceptionally rare subtype, with limited documented cases in the English literature.
Maxillomandibular lesions in children present unique diagnostic and therapeutic challenges.

Observation:

A pediatric patient presented with a rare telangiectatic osteosarcoma of the mandible.
This represents the first reported instance of this specific tumor type in the mandibular bone of a child.
The rarity of this condition underscores the need for comprehensive case reporting and analysis.

Findings:

The telangiectatic osteosarcoma in the pediatric mandible was successfully treated with hemimandibulectomy.
The patient has remained disease-free for seven years post-treatment, indicating favorable long-term outcomes.
This case contributes valuable data on the management of rare pediatric jaw tumors.

Implications:

This case highlights the potential for successful surgical management of rare pediatric mandibular tumors.
Long-term follow-up is crucial for assessing outcomes in patients with telangiectatic osteosarcoma.
Further research into rare osteosarcoma variants in pediatric populations is warranted to improve treatment strategies.