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Updated: Apr 21, 2026

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Elongation of pulse width as an augmentation strategy in electroconvulsive therapy
Hirotsugu Kawashima1, Taro Suwa2, Toshiya Murai2
1Department of Psychiatry, Toyooka Hospital, Hyogo, Japan.
Abstract:
Inducing adequate therapeutic seizures during electroconvulsive therapy is sometimes difficult, even at the maximum stimulus charge, due to a high seizure threshold. Here, we describe two patients with very poor seizure responses at the maximum charge using conventional stimulus parameters in whom responses were successfully augmented by widening the pulse width at the same or even lower stimulus charge. This strategy could be an additional option for seizure augmentation in clinical practice. The potential clinical utility of stimulus parameter modifications should be further investigated.
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