Preparation and pharmaceutical evaluation of nicotinamide stick for eradication of Staphylococcus epidermidis

Staphylococcus epidermidis is a part of the skin's normal flora that can cause acne. This study was designed to evaluate the efficacy of nicotinamide as a stick in eradication of staphylococcus.

For evaluating of Anti-microbial effect on S. epidermidis used well plate method. We chose five plates for nicotinamide and five for mupirocin. The zones of inhibition were measured and compared.

The results showed nicotinamide stick had anti-microbial effects, but in comparison to mupirocin it was significantly less (P = 0.003).

Nicotinamide stick was made and evaluated. This study showed that nicotinamide had anti-microbial effect on staphylococcus.