[Short bowel: from resection to transplantation]

Area of Science:

• Gastroenterology
• Surgical Sciences
• Transplantation Medicine

Background:

• Short bowel syndrome (SBS) results from extensive loss of small intestine surface area.
• Complications include malabsorption, malnutrition, dehydration, and metabolic issues.
• Often occurs post-resection, intrinsic disease, or surgical bypass.

Purpose of the Study:

• To review the key aspects of short bowel syndrome (SBS).
• To highlight current treatment strategies and outcomes.
• To discuss the role of bowel transplantation (BT) in managing irreversible intestinal failure.

Main Methods:

• Literature review of short bowel syndrome (SBS) and bowel transplantation (BT).
• Analysis of recent outcomes and survival rates.
• Evaluation of treatment efficacy and patient autonomy.

Main Results:

• Short bowel syndrome (SBS) leads to severe malabsorption and malnutrition.
• Parenteral nutrition has limitations for long-term management.
• Bowel transplantation (BT) shows high survival rates and promotes digestive autonomy.

Conclusions:

• Bowel transplantation (BT) is a viable first-line therapy for selected SBS patients.
• Successful BT can lead to complete digestive autonomy.
• Individualized nutritional support remains crucial in SBS management.