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[The relationship between rhinitis and asthma: is that all?]
Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|November 4, 2014
Summary
Allergic rhinitis and asthma are linked, with rhinitis potentially causing asthma. Treating rhinitis improves asthma symptoms and lung function, supporting the "one airway, one disease" concept.
Area of Science:
- Respiratory Medicine
- Immunology
- Allergy
Context:
- Allergic rhinitis and asthma frequently coexist, exceeding chance occurrence.
- Rhinitis is increasingly recognized as a significant risk factor for asthma development.
- The
- one airway, one disease
- hypothesis posits a unified pathophysiology for upper and lower airway inflammatory conditions.
Purpose:
- To review epidemiological, genetic, and clinical evidence linking allergic rhinitis and asthma.
- To explore the mechanisms underlying nose-lung interactions in respiratory diseases.
- To evaluate treatment strategies supporting the
- one airway, one disease
- model.
Summary:
- Epidemiological and clinical studies demonstrate a strong association between rhinitis and asthma.
- Immunopathological and physiological evidence suggests a shared inflammatory pathway affecting both airways.
- Treating allergic rhinitis positively impacts asthma control, lung function, and bronchial hyperresponsiveness.
Impact:
- This review consolidates evidence for a systemic inflammatory process affecting both upper and lower airways.
- It highlights the therapeutic implications of treating rhinitis for asthma management.
- Understanding nose-lung interactions can refine diagnostic and treatment approaches for comorbid respiratory conditions.
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