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Congenital primary cutaneous anaplastic large-cell lymphoma: a case report
An Na Seo1, Seok-Jong Lee, Yoon Hyuk Choi
1Departments of *Pathology, †Dermatology, and ‡Plastic and Reconstructive Surgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea; and §Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract:
Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is the second most common type of primary cutaneous T-cell lymphoma. The median age of onset of C-ALCL is 60 years. Presented here is a case of congenital CD30-positive (CD30(+)) primary C-ALCL in a 10-day-old neonate who presented with a large erythematous indurative plaque in the right postauricular area. A systemic workup of the patient excluded other potential causes. The neonate was treated with wide excision, but chemotherapy or radiation therapy was not administered, as the patient's parents did not consent to such treatment. The patient has been monitored for 30 months after excision and there has been no disease recurrence. C-ALCL rarely occurs in children, and to the best of our knowledge, this is the first reported case of a neonate with congenital primary C-ALCL.
