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LOX-1 unlocks human plasma cell potential
1Immunology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, UNSW Australia, 390 Victoria Street, Darlinghurst NSW 2010, Australia.
Immunity
|November 5, 2014
Abstract:
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is best known for promoting atherosclerosis. In this issue of Immunity, Joo et al. (2014) find that dendritic cells triggered through LOX-1 can directly support plasmablast production via the production of the cytokines APRIL and BAFF.

