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Impact of maternal and paternal preconception health on birth outcomes using prospective couples' data in Add Health
Jennifer L Moss1, Kathleen Mullan Harris
1Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina, CB 7440, Chapel Hill, NC, 27599-7440, USA, jlmoss@email.unc.edu.
Insights
Both maternal and paternal preconception health significantly impact infant birth outcomes like birthweight and gestational age. Promoting healthy habits and managing conditions like diabetes before conception is crucial for better birth results.
Area of Science:
- Reproductive Health
- Perinatal Epidemiology
- Public Health
Background:
- Previous research indicates parental health influences newborn outcomes.
- Studies often focus retrospectively, limiting prospective insights into preconception health impacts.
- Understanding prospective preconception health is vital for future child well-being.
Purpose of the Study:
- To prospectively examine the influence of maternal and paternal preconception health on infant birthweight and gestational age.
- To identify specific parental health conditions and behaviors affecting key birth outcomes.
- To provide evidence for targeted preconception health interventions.
Main Methods:
- Utilized data from the National Longitudinal Study of Adolescent Health (Add Health).
- Included interviews with participants and their partners (2001-02) and follow-up interviews (2008).
- Regressed birth outcomes (N=372 infants) on preconception health data from non-pregnant partners.
Main Results:
- Maternal diabetes or high blood pressure and monthly alcohol consumption were linked to higher birthweight.
- Paternal diabetes was associated with lower infant birthweight.
- Paternal diabetes and higher fast food consumption correlated with lower gestational age.
Conclusions:
- Both maternal and paternal preconception health status significantly affect infant birthweight and gestational age.
- Interventions should prioritize preventing diabetes and hypertension.
- Reducing alcohol and fast food consumption pre-conception is recommended.
Purpose:
Retrospective studies of preconception health have demonstrated that parents' health conditions and behaviors can impact a newborn's birth outcomes and, subsequently, future health status. This study sought to examine the impact of preconception health, measured prospectively, among both mothers and fathers, on two important birth outcomes: birthweight and gestational age.
Methods:
Data came from Add Health (the National Longitudinal Study of Adolescent Health), which included interviews with original participants and a subsample of their partners in 2001-02. In 2008, the original respondents again completed an interview for Add Health. For 372 eligible infants born to these couples, birth outcomes (measured in 2008) were regressed on preconception health conditions and behaviors among non-pregnant heterosexual partners (measured in 2001-02).
Results:
Mean birthweight was 3,399 g, and mean gestational age was 39 weeks. Birthweight was higher for infants born to mothers with diabetes or high blood pressure, and for mothers who drank alcohol at least once per month, and lower for infants born to fathers with diabetes (p < 0.05). Infant gestational age was marginally lower for infants born to mothers with higher levels of depression (p < 0.10), and lower for infants born to fathers with diabetes and with higher levels of fast food consumption (p < 0.05).
Conclusions:
Both maternal and paternal preconception health conditions and behaviors influenced infant birth outcomes. Interventions to promote preconception health should focus on prevention of diabetes and high blood pressure, as well as minimizing consumption of alcohol and fast food.
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