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Updated: Apr 21, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
The impact of genomics on public health practice
H Burton1, C Jackson2, I Abubakar3
1PHG Foundation, 2 Worts Causeway, Cambridge CB1 8RN, UK hilary.burton@phgfoundation.org.
Introduction:
Genomic science is developing rapidly, and engagement of public health professionals will be necessary to appraise new technologies and use them effectively.
Sources Of Data:
We use established domains of public health and draw on the literature and expert knowledge to illustrate how genomic technologies give rise to new applications.
Areas Of Agreement:
Genomic technologies are useful in rare inherited disease, including population screening programmes, in health care and for surveillance, diagnosis and treatment of infectious disease.
Areas Of Controversy:
It is less clear when and how genetic susceptibility testing will be used for common chronic disease prevention or protection from environmental hazards.
Growing Points:
Developments in public health practice will be necessary to ensure rapid and effective implementation of genomic science.
Areas Timely For Developing Research:
Public health researchers should address how to accelerate the implementation of genomics for health benefit in developed and developing countries.
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