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Updated: Apr 21, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Functionalised gold and titania nanoparticles and surfaces for use as antimicrobial coatings
Sacha Noimark1, Kristopher Page, Joseph C Bear
1Materials Chemistry Research Centre, Department of Chemistry, University College London, 20 Gordon St, London, WC1H 0AJ, UK. i.p.parkin@ucl.ac.uk.
Abstract:
We report the preparation, characterisation and antimicrobial functional testing of various titanium dioxide and gold modified titanium dioxide nanoparticles embedded into a polysiloxane polymer by a swell dip-coating procedure. We show that the surfaces are effective in killing both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria under different lighting conditions. The presence of the nanoparticles was of critical importance in improving the functional properties of the surface. These materials have the potential to reduce hospital-acquired infection, by killing bacteria on the polymer surface.

