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Updated: Apr 21, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Dynamic tumor tracking using the Elekta Agility MLC.

Martin F Fast¹, Simeon Nill¹, James L Bedford¹

¹Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London SM2 5NG, United Kingdom.

Medical Physics

|November 6, 2014

Summary

This summary is machine-generated.

The Elekta Agility multileaf collimator (MLC) shows promising performance for real-time tumor tracking, with measured latencies and geometric accuracy suitable for clinical applications.

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Area of Science:

Medical Physics
Radiation Oncology
Image-Guided Therapy

Background:

Real-time tumor tracking is crucial for precise radiation delivery.
The Elekta Agility multileaf collimator (MLC) is a key component in modern radiotherapy systems.
Evaluating MLC performance in dynamic tracking scenarios is essential for clinical implementation.

Purpose of the Study:

To assess the performance of the Elekta Agility MLC for dynamic real-time tumor tracking.
To quantify the system latency and geometric accuracy of the MLC during motion.
To investigate the impact of different motion components (leaves, jaws, dynamic leaf guides) on tracking performance.

Main Methods:

Developed new control software to dynamically program MLC and jaw movements based on target trajectory.
Utilized a motion platform for dynamic tracking experiments with sinusoidal trajectories at varying frequencies (20-40 Hz).
Acquired MV portal images to extract system latency and geometric tracking accuracy (RMSE) for leaf-only, jaw + leaf, and DLG + leaf motion scenarios.

Main Results:

System latency demonstrated a dependence on target position reporting frequency.
Leaf adjustment latency was measured at 38 ± 3 ms (v ≤ 13 mm/s).
Tracking accuracy (RMSE) ranged from 0.6-1.5 mm for leaf motion and 0.7-3.4 mm for combined motions, varying with speed and frequency.

Conclusions:

The Elekta Agility MLC's latency and geometric accuracy have been quantified.
The system performance is suitable for integration into clinical real-time tumor tracking applications.
This evaluation facilitates the future use of the Agility MLC in advanced radiotherapy.