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Updated: Jul 31, 2026

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
Serological findings in a child with paroxysmal cold haemoglobinuria
Eduardo J Salido1, Valentín Cabañas1, Mercedes Berenguer1
1Hematology Department, Hematopoietic Transplant and Cellular Therapy Unit, Virgen de la Arrixaca Clinical University Hospital, IMIB-Arrixaca, University of Murcia, Carretera Madrid-Cartagena, s/n, El Palmar, 30120 Murcia, Spain.
Abstract:
PCH is a rare autoimmune hemolytic anemia (AIHA) but is one of the most common causes of AIAH in children. For the diagnosis, it is important to perform the appropriate methods of serological investigation and show the typical biphasic reaction. This is a case report of a child who presented with features of haemolysis and was diagnosed with PCH of this way.

