Related Experiment Video

Updated: Apr 21, 2026

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method
08:07

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method

Published on: July 4, 2021

2.8K

Clinical characteristics of cerebral venous thrombosis in a single center in Korea

Dong Sun Park1, Chang Taek Moon1, Young Il Chun1

  • 1Department of Neurosurgery, Konkuk University Medical Center, Seoul, Korea.

Journal of Korean Neurosurgical Society
|November 6, 2014
PubMed

Insights

This study on cerebral venous thrombosis (CVT) in Korea found it more common in men, with prothrombotic conditions being the leading cause. Hemorrhagic infarction was significantly linked to prothrombotic factors.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Thrombosis Research

Background:

  • Cerebral venous thrombosis (CVT) is a rare but serious condition with variable clinical presentations.
  • Understanding the specific characteristics of CVT in different populations is crucial for diagnosis and management.

Purpose of the Study:

  • To investigate the clinical features of cerebral venous thrombosis (CVT) in a Korean single-center cohort.
  • To compare these findings with international CVT studies.

Main Methods:

  • Retrospective analysis of 36 patients diagnosed with CVT between August 2005 and May 2013.
  • Data collected included demographics, disease stage, pathogenesis, location, laboratory and radiological findings, and treatments.
  • Comparison of results with existing literature from Europe and America.

Main Results:

  • The study included 21 men and 15 women, with a mean age of 46.9 years.
  • Prothrombotic conditions were the most frequent cause (22.2%).
  • Hemorrhagic infarction occurred in 36.1% of patients, with higher proportions in cortical and deep venous thrombosis, and significantly in the prothrombotic group (p=0.016).

Conclusions:

  • Cerebral venous thrombosis in this Korean cohort was more prevalent in men, with a peak incidence in the sixth decade.
  • Prothrombotic conditions were the primary identified cause.
  • Findings suggest potential demographic and etiological differences compared to Western populations, particularly regarding gender prevalence and hemorrhagic infarction association.
Abstract

Keywords:
Cerebral venous thrombosisHemorrhagic infarctionProthrombotic condition

More Related Videos

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli13:10

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli

Published on: September 25, 2016

9.4K
Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke06:37

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

1.5K

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
466
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
2
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
7
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
5
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
796
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
4