Related Experiment Video
Updated: Apr 21, 2026

06:55
Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
20.8K
Nutrition and Chronic Wounds
Joseph Andrew Molnar1, Mary Jane Underdown2, William Andrew Clark3
1Department of Plastic and Reconstructive Surgery, Wake Forest University School of Medicine , Winston-Salem, North Carolina.
Advances in Wound Care
|November 6, 2014
Summary
Addressing malnutrition in geriatric patients is crucial for chronic wound healing. Nutritional support and targeted supplements can significantly improve patient outcomes.
Area of Science:
- Geriatric Medicine
- Nutritional Science
- Wound Care
Background:
- Malnutrition is prevalent in geriatric populations, even in developed countries, impacting chronic wound management.
- Understanding the epidemiology and causes of malnutrition is essential for effective intervention.
- Existing knowledge on nutritional support often stems from trauma management, requiring adaptation for chronic wounds.
Approach:
- Review recent research on malnutrition in developed and developing countries.
- Analyze the physiological and sociological factors contributing to malnutrition.
- Investigate the biochemical effects of nutrient deficiencies and supplementation.
Key Points:
- Nutritional status assessment is critical before implementing supplementation strategies.
- Specific nutrients, including macronutrients and micronutrients, play vital roles in wound healing.
- Pharmacological effects of certain nutrients may enhance healing beyond standard recommendations.
Conclusions:
- Basic nutrition and appropriate supplementation can aid chronic wound healing in geriatric patients.
- Future research should focus on the distinct biochemical and physiological needs of chronic wounds regarding specific supplements like antioxidants, vitamin A, and vitamin D.
Related Concept Videos
Phases of Wound Repair
7.9K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
7.9K
Diabetic Foot Ulcer
5
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
5
Chronic Kidney Disease III: Interprofessional Care
670
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
670
Chronic Kidney Disease IV: Nursing Management
671
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
671
Healing II: Complications
23
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
23
Peripheral Artery Disease IV: Nursing Management
676
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
676

