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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Whole Body Regeneration01:33

Whole Body Regeneration

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Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
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Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

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Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
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Adult Stem Cells01:33

Adult Stem Cells

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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Propagation of Human Embryonic Stem ES Cells
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Propagation of Human Embryonic Stem ES Cells

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Centre for human development, stem cells & regeneration.

Richard O C Oreffo

    Regenerative Medicine
    |November 6, 2014
    PubMed
    Summary
    This summary is machine-generated.

    The Centre for Human Development, Stem Cells and Regeneration (CHDSCR) conducts fundamental and translational research. It focuses on early development and stem cells for patient benefit, utilizing multidisciplinary programs and clinical infrastructure.

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    Area of Science:

    • Regenerative Medicine
    • Developmental Biology
    • Stem Cell Research

    Background:

    • The Centre for Human Development, Stem Cells and Regeneration (CHDSCR) was established in 2004 at the University of Southampton.
    • It operates as a cross-disciplinary research and translational program within the Faculty of Medicine.

    Purpose of the Study:

    • To conduct fundamental research into early development and stem cells.
    • To perform applied translational research aimed at patient benefit.

    Main Methods:

    • Harnessing multidisciplinary research programs.
    • Leveraging the translational strength of the Faculty of Medicine.
    • Utilizing an innovative Stem Cell PhD program and clinical infrastructure.

    Main Results:

    • The Centre fosters vibrant and thriving research programs.
    • Integration of fundamental and translational research approaches.
    • Development of enterprise initiatives.

    Conclusions:

    • CHDSCR effectively integrates basic science with clinical application.
    • The Centre is dedicated to advancing human development and regenerative medicine.
    • Multidisciplinary collaboration and infrastructure support the Centre's vision.