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Updated: Apr 21, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Allergic contact dermatitis to 2-octyl cyanoacrylate
Casey Bowen1, Jeff Bidinger, Chad Hivnor
1Department of Dermatology, San Antonio Military Medical Center South, 2200 Bergquist Dr, Ste 1, Lackland AFB, TX 78236, USA. caseybowen.2@us.af.mil.
Abstract:
Cyanoacrylates are widely used as topical skin adhesives in emergency departments, clinics, and operating rooms. We report 4 patients who developed allergic contact dermatitis (ACD) following postsurgical closure with 2-octyl cyanoacrylate. These patients were challenged with a novel method of use testing to confirm sensitivity to 2-octyl cyanoacrylate. The popularity of skin adhesives makes this emerging allergen worthy of examination. It is possible that cyanoacrylate allergy currently is underrecognized.
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