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Updated: Apr 21, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Choroidal metastases of choriocarcinoma
Albert Hazan1, Matthew S J Katz, Henry Leder
1*Albert Einstein College of Medicine; †Department of Ophthalmology, Montefiore Medical Center, Bronx, New York; and ‡Department of Ophthalmology, Jacobi Medical Center.
Purpose:
We present here a patient with choroidal metastases of choriocarcinoma; her clinical and pathologic findings are described.
Methods:
Retrospective case study with fundus photographs. A 23-year-old woman presented with a dense vitritis, retinal detachment, and underlying chorioretinal lesions. Systemic workup revealed choriocarcinoma with disseminated metastases.
Results:
This patient's underlying malignancy was unrecognized at initial presentation to ophthalmology. This case reaffirms the importance of thorough systemic investigation for atypical intraocular lesions.
Conclusion:
Adult intraocular neoplasms are most commonly metastases from distal primary malignancies. The same holds true for uveal malignancies. In many uveal malignancies, the intraocular lesion is a harbinger for an, as yet, undiscovered underlying systemic malignancy.

