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Updated: Apr 21, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Progress on genetic basis of primary aldosteronism]
Hong Zhang1, Wei Gu1, Min-yue Jia1
1Department of Endocrinology,Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China.
Abstract:
It has been proven that familial aldosteronism type I is related to 11-beta hydroxylase (CYP11B1)/aldosterone synthase (CYP11B2) chimeric genes. In recent years, accumulated evidences indicate that the genetic basis of primary aldosteronism may involve chromosome 7p22 candidate genes, polymorphisms of CYP11B1 and CYP11B2 genes, mutations of ion channel- related KCNJ5, ATP1A1, CACNA1D genes. The article reviews the progress on genetic basis of primary aldosteronism.
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