Identifying predictors of blood pressure control in the Lebanese population - a national, multicentric survey --
Samir G Mallat1, Serena Abu Samra, Fariha Younes
1Department of Internal Medicine, American University of Beirut, Riad El-Solh, P,O, Box 11-0236, Beirut 11072020, Lebanon. sm104@aub.edu.lb.
Insights
Achieving early blood pressure control and using combination therapy are key to better hypertension management. Diabetes is a significant predictor of poor blood pressure control, highlighting areas for targeted interventions.
Area of Science:
- Cardiology
- Public Health
- Clinical Medicine
Background:
- Blood pressure (BP) control remains a challenge in Lebanon, with limited understanding of factors influencing it.
- Effective hypertension management necessitates identifying patient characteristics and predictors of uncontrolled BP.
Purpose of the Study:
- To determine predictors of BP control in patients followed for up to 6 months.
- To identify factors associated with both improved and poor BP control.
Main Methods:
- The I-PREDICT study involved 988 patients with newly diagnosed or uncontrolled hypertension.
- Socio-demographic and clinical data were analyzed prospectively.
- Agreement between physician perceptions and JNC VII guidelines for BP control was assessed.
Main Results:
- Diabetes was a significant predictor of poor BP control (OR=0.15 at 6 months).
- Early BP control at 1 month (OR=10.39) and combination therapy (OR=15.14) predicted better 6-month control.
- In diabetic patients, diet adherence and BP control at V2 were associated with better outcomes, while economic class predicted poor control.
- BP control rates significantly improved from 44.08% at 1 month to 67.52% at 6 months (P=0.001).
Conclusions:
- Early BP control and combination therapy are crucial for improved hypertension management.
- Diabetes is a key factor associated with poor BP control, requiring targeted strategies.
- A notable discrepancy exists between JNC VII guidelines and clinical practice regarding BP control assessment.
Background:
Blood Pressure (BP) is not well controlled and factors that predict BP control are not well identified in Lebanon. Improvement of hypertension management requires an understanding of patients' characteristics and factors associated with uncontrolled BP. This national, multicentric, observational prospective study was designed to determine the predictors of BP control in patients followed up to 6 months.
Methods:
I-PREDICT study was conducted on 988 patients with newly diagnosed or uncontrolled hypertension. Socio-demographic and clinical characteristics were analyzed. The level of agreement between doctors' perceptions on BP control status and JNC VII guidelines was analyzed.
Results:
The predictor associated with poor BP control was diabetes (OR = 0.17, CI = 0.10-0.28 at month-1; OR = 0.15, CI = 0.10-0.24 at month-6). The predictors associated with better BP control at month-6 were the early control of BP at month-1 (OR = 10.39, CI = 6.18-17.47) and combination therapy prescribed at baseline and month-1 (OR = 15.14, CI = 1.09-208.46, P = 0.04). In the sub-group of diabetes, the predictors that were associated with better BP control at 6 months were following diet at V1 (OR = 2.27, CI = 1.01 to 5.12) and BP control at V2 (OR = 7.34, CT = 3.83 to 14.07). The predictors that were associated with poor BP control at 6 months were middle economic class (OR = 0.036, CI = 0.16-0.94) and upper economic class (OR = 0.036; CI = 0.13-0.93).The rate of BP control was significantly higher at month 6 versus month 1 (67.52% vs 44.08%, P = 0.001). Additional analysis showed poor agreement between the doctors' perceptions on BP control status and the guidelines.
Conclusions:
Reaching an early BP control and combination therapy were significant predictors of better BP control, whereas diabetes was a significant predictor of poor BP control. A poor agreement between JNC VII guidelines and clinical practice was observed. I-PREDICT study identified factors that can be targeted for improving BP control.
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