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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
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Methamphetamine psychosis: epidemiology and management
Suzette Glasner-Edwards1, Larissa J Mooney
1Integrated Substance Abuse Programs, David Geffen School of Medicine at UCLA, Semel Institute for Neuroscience and Human Behavior, 1640 S. Sepulveda Blvd., Suite 120, Los Angeles, CA, 90025, USA, sglasner@ucla.edu.
CNS Drugs
|November 7, 2014
Summary
Methamphetamine use frequently causes psychosis, affecting up to 40% of users. Psychosocial treatment for dependence is key to reducing psychosis, alongside managing co-occurring disorders to prevent relapse.
Area of Science:
- Psychiatry
- Neuroscience
- Addiction Medicine
Background:
- Methamphetamine (MA) use is linked to psychosis in up to 40% of users.
- Acute psychosis can manifest as agitation, violence, and delusions, requiring crisis intervention.
- Persistent psychosis can mimic primary psychotic disorders, complicating diagnosis.
Purpose of the Study:
- To explore the challenges in diagnosing primary vs. substance-induced psychosis in MA users.
- To outline optimal diagnostic and treatment strategies for MA-induced psychosis.
- To emphasize the role of psychosocial interventions and relapse prevention.
Main Methods:
- Differential diagnosis using temporal relationship to MA use.
- Psychodiagnostic assessment instruments and urine toxicology assays.
- Collateral clinical data from family and close contacts.
Main Results:
- Accurate diagnosis is achievable through comprehensive assessment.
- Acute psychosis may resolve with abstinence or require antipsychotics/benzodiazepines.
- Psychosocial treatment for MA dependence is the first-line approach.
Conclusions:
- Psychosocial treatment for MA dependence is crucial for reducing psychosis rates.
- Relapse prevention is vital for managing recurrent psychosis.
- Addressing co-occurring disorders aids in preventing MA use relapse.
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