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Updated: Apr 21, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
Published on: March 26, 2018
[Therapy of aortic valve stenosis]
1Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland, widder.julian@mh-hannover.de.
Insights
Calcific aortic stenosis, a common heart valve disease, requires valve replacement when severe. Treatment options include surgical replacement or transcatheter aortic valve implantation for high-risk patients.
Area of Science:
- Cardiology
- Valvular Heart Disease
- Geriatric Medicine
Background:
- Calcific aortic stenosis is the most prevalent heart valve disorder in Western populations.
- It is a degenerative, progressive condition common in the elderly, with rising incidence due to demographic shifts.
- Currently, no medical therapy exists, making valve replacement the sole treatment for severe cases.
Purpose of the Study:
- To review the diagnostic criteria and therapeutic options for calcific aortic stenosis.
- To discuss the management of complex cases, including low flow, low gradient aortic stenosis.
- To outline treatment indications based on symptoms and patient risk stratification.
Main Methods:
- Echocardiography is the primary diagnostic tool for assessing aortic stenosis severity and valve morphology.
- Diagnostic criteria for severe aortic stenosis include valve area <1.0 cm², valve index <0.6 cm²/m², mean gradient >40 mmHg, and peak velocity >4.0 m/s.
- Patient management is guided by symptom onset and progression, with regular reevaluation for asymptomatic individuals.
Main Results:
- Severe aortic stenosis is defined by specific echocardiographic parameters.
- Asymptomatic patients generally have a favorable prognosis but require monitoring.
- Symptomatic patients experience a significant decline in prognosis, necessitating valve replacement.
Conclusions:
- Surgical valve replacement is the gold standard treatment for aortic stenosis.
- Transcatheter aortic valve implantation (TAVI) is the established standard therapy for high-risk patients, including the elderly and those with severe comorbidities.
- Timely diagnosis and appropriate intervention are crucial for managing calcific aortic stenosis.
Abstract:
Calcific aortic stenosis is the most frequent valve disorder in the western world. It is a degenerative and chronic progressive disease in the elderly with increasing prevalence due to the demographic development in the population. As there is no medical therapy, the only option in severe aortic stenosis is valve replacement. Echocardiography is the diagnostic tool to assess aortic stenosis severity and morphology of the valve. Aortic stenosis is severe if the valve area is <1.0 cm(2), valve index <0.6 cm(2)/m(2) body surface, mean gradient >40 mmHg, and peak velocity >4.0 m/s. The entity of low flow, low gradient aortic stenosis is complex, and diagnosis and therapy are still challenging. Asymptomatic patients have a good prognosis, but must be reevaluated on a regular basis for the onset of symptoms or signs of progression. If one of the classical symptoms dyspnea and fatigue, angina pectoris or syncope occurs prognosis worsens dramatically and valve replacement is indicated. Gold standard therapy for aortic stenosis is surgical valve replacement. For high-risk patients (older age and severe comorbidities), transcatheter aortic valve implantation (TAVI) is established as standard therapy.
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