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Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

5
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
5
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

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Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
9
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

7
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
7
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

5
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
5

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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
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Cerebral microbleeds and functional outcomes after ischemic stroke.

Tae-Won Kim1, Seung-Jae Lee2, Jaseong Koo1

  • 11Department of Neurology,College of Medicine,Catholic University of Korea,Seoul,Korea.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|November 7, 2014
PubMed
Summary

Infratentorial cerebral microbleeds (CMBs) are linked to worse functional recovery after ischemic stroke, both early and long-term. The presence of these CMBs can predict poor outcomes.

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Area of Science:

  • Neurology
  • Neuroimaging
  • Stroke Medicine

Background:

  • The relationship between cerebral microbleeds (CMBs) and functional recovery post-ischemic stroke remains unclear.
  • Understanding this association is crucial for predicting patient outcomes.

Purpose of the Study:

  • To investigate the association between CMBs and functional outcomes after acute ischemic stroke.
  • To determine if CMBs can predict long-term functional recovery.

Main Methods:

  • Patients with acute ischemic stroke were categorized into good and poor functional outcome groups.
  • Modified Rankin Scale scores were used for outcome assessment at discharge and 6 months.
  • Logistic regression analysis identified predictors of poor functional outcomes, including CMBs and white matter hyperintensities.

Main Results:

  • Cerebral microbleeds (CMBs) were associated with poor functional outcomes at discharge and 6 months post-stroke.
  • Infratentorial CMBs specifically predicted worse functional outcomes in both early and chronic phases.
  • Patients with poor functional outcomes exhibited a higher burden of CMBs at 6 months.

Conclusions:

  • Infratentorial CMBs are significant predictors of worse functional outcomes after acute ischemic stroke.
  • These findings highlight the prognostic value of infratentorial CMBs for both short-term and long-term recovery.