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Cerebral microbleeds and functional outcomes after ischemic stroke

Tae-Won Kim1, Seung-Jae Lee2, Jaseong Koo1

  • 11Department of Neurology,College of Medicine,Catholic University of Korea,Seoul,Korea.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|November 7, 2014
PubMed
Abstract

Insights

Infratentorial cerebral microbleeds (CMBs) are linked to worse functional recovery after ischemic stroke, both early and long-term. The presence of these CMBs can predict poor outcomes.

Area of Science:

  • Neurology
  • Neuroimaging
  • Stroke Medicine

Background:

  • The relationship between cerebral microbleeds (CMBs) and functional recovery post-ischemic stroke remains unclear.
  • Understanding this association is crucial for predicting patient outcomes.

Purpose of the Study:

  • To investigate the association between CMBs and functional outcomes after acute ischemic stroke.
  • To determine if CMBs can predict long-term functional recovery.

Main Methods:

  • Patients with acute ischemic stroke were categorized into good and poor functional outcome groups.
  • Modified Rankin Scale scores were used for outcome assessment at discharge and 6 months.
  • Logistic regression analysis identified predictors of poor functional outcomes, including CMBs and white matter hyperintensities.

Main Results:

  • Cerebral microbleeds (CMBs) were associated with poor functional outcomes at discharge and 6 months post-stroke.
  • Infratentorial CMBs specifically predicted worse functional outcomes in both early and chronic phases.
  • Patients with poor functional outcomes exhibited a higher burden of CMBs at 6 months.

Conclusions:

  • Infratentorial CMBs are significant predictors of worse functional outcomes after acute ischemic stroke.
  • These findings highlight the prognostic value of infratentorial CMBs for both short-term and long-term recovery.

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