Selective ultrasound screening is inadequate to identify patients who present with symptomatic adult acetabular dysplasia
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Published on: April 19, 2024
Ernest L Sink1, Benjamin F Ricciardi, Katrina Dela Torre
1Center for Hip Pain and Preservation, Hospital for Special Surgery, 541 East 71th Street, 10021, New York, NY, USA, sinke@hss.edu.
Insights
Most adults with hip dysplasia were not identified by newborn screening. Current selective ultrasound screening guidelines miss many cases, suggesting a need for revised screening protocols to prevent adult hip problems.
Area of Science:
- Orthopedics
- Developmental Dysplasia of the Hip (DDH)
- Pediatric Orthopedics
Background:
- Neonatal screening for developmental dysplasia of the hip (DDH) aims to prevent late surgical interventions.
- However, many individuals with acetabular dysplasia at skeletal maturity are not diagnosed with DDH in infancy.
- Selective ultrasound screening for neonatal hip instability may not prevent adult-onset hip dysplasia.
Purpose of the Study:
- To determine the prevalence of risk factors for DDH in skeletally mature patients with symptomatic acetabular dysplasia.
- To assess if these patients would have met criteria for selective ultrasound screening during infancy.
Main Methods:
- A registry of 68 skeletally mature patients undergoing corrective osteotomy for acetabular dysplasia was analyzed.
- Evaluated risk factors included sex, family history, birth complications (breech, delivery method), birth order, and prior hip treatments.
- Preoperative radiographic measurements (CEA, Tönnis grade/angle) were recorded.
Main Results:
- The study included 67 females and 1 male, none with prior DDH diagnosis or treatment.
- A significant majority (85.3%) did not meet selective ultrasound screening guidelines based on a stable neonatal exam.
- Among those outside screening criteria, 98.5% were female, 52.9% were firstborn, and 36.8% had a family history of hip osteoarthritis.
Conclusions:
- Most patients with symptomatic acetabular dysplasia at skeletal maturity would not have qualified for selective ultrasound screening in the USA under current guidelines.
- This highlights a potential gap in early detection of hip dysplasia that can lead to adult-onset acetabular dysplasia.
Purpose:
One goal of neonatal screening for developmental dysplasia of the hip (DDH) is the prevention of late surgery. However, the majority of patients with acetabular dysplasia at skeletal maturity are not diagnosed with DDH during infancy. Selective ultrasound screening may identify patients with neonatal hip instability, but may be ineffective for the prevention of dysplasia presenting in adulthood. The purpose of this study is to identify the prevalence of risk factors for DDH that would have warranted selective ultrasound screening in patients with symptomatic acetabular dysplasia after skeletal maturity.
Methods:
A prospective hip specialty center registry was used to identify 68 consecutive skeletally mature patients undergoing corrective osteotomy for symptomatic acetabular dysplasia. Risk factors for DDH evaluated in all patients included sex, family history of hip osteoarthritis or DDH, breech, method of delivery, previous hip treatments, and birth order. Radiographs [lateral center edge angle (CEA), anterior CEA, Tönnis grade, and Tönnis angle] were measured preoperatively.
Results:
Sixty-seven females and one male were identified. No patients were previously diagnosed with DDH or received treatment for their hips. The majority of patients (85.3 %) did not meet selective ultrasound screening guidelines following a stable neonatal hip exam and, therefore, would not have been screened in a selective screening program. Of the findings outside of screening guidelines, 98.5 % were females, 52.9 % were first born, and 36.8 % had a family history of hip osteoarthritis.
Conclusions:
The majority (85.3 %) of patients with symptomatic acetabular dysplasia at skeletal maturity would not have met current recommendations for selective ultrasound screening in the USA had they been born today.
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