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Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes
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Fluorescent probes for biomedical applications (2009-2014).
Sona Warrier1, Prashant S Kharkar
1Department of Pharmaceutical Chemistry, Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management (SPPSPTM), SVKM's NMIMS, V. L. Mehta Road, Vile Parle (West), Mumbai 400-056, India.
Pharmaceutical Patent Analyst
|November 7, 2014
Summary
This review covers small-molecule fluorescent probes, focusing on patents from 2009-2014. It details their preparation and biomedical applications, highlighting ongoing innovation in this vital life science tool.
Area of Science:
- Life Sciences
- Biomedical Research
- Chemical Biology
Background:
- Fluorescent probes are crucial tools in life sciences for interpreting biological phenomena.
- They are widely used in pharmaceutical research, clinical diagnostics, and high-throughput screening.
- Continuous innovation seeks novel fluorescent probes with improved chemistry to overcome current limitations.
Purpose of the Study:
- To review patents and patent applications for small-molecule fluorescent probes.
- To cover the period from January 2009 to March 2014.
- To classify these innovations based on preparation and biomedical applications.
Main Methods:
- Systematic review of patent literature.
- Classification of patents based on probe preparation.
- Classification of patents based on biomedical applications.
Main Results:
- Analysis of patent trends in small-molecule fluorescent probe development.
- Identification of key areas in probe preparation and application.
- Overview of advancements in fluorescent probe technology during the specified period.
Conclusions:
- The period 2009-2014 saw significant patent activity in small-molecule fluorescent probes.
- Ongoing research focuses on novel chemistries for enhanced probe performance.
- These innovations continue to expand the utility of fluorescent probes in biomedical research.
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