Related Experiment Video
Updated: Apr 21, 2026
Isolation, Characterization and MicroRNA-based Genetic Modification of Human Dental Follicle Stem Cells
Published on: November 16, 2018
Hyperplastic dental follicle: a case report and literature review
Ligia Buloto Schmitd1, Diego Maurício Bravo-Calderón2, Cleverson Teixeira Soares3
1Pathology Division, Department of Stomatology, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla 9-75, 17012-901 Bauru, SP, Brazil ; ESFA Dental School, Rua Bernardino Monteiro 700, 29650-000 Santa Teresa, ES, Brazil.
Abstract:
Hyperplastic dental follicle is an odontogenic hamartomatous lesion associated with delayed or tooth eruption failure in young patients. The occurrence of this pericoronal dental lesion may be single or multiple and it seems to be more frequent than literature has reported. We present a literature review focusing on the etiopathogenesis and clinicopathological features of this hamartomatous lesion in young patients. In addition, we reported a case of hyperplastic dental follicle causing delayed tooth eruption of 14-year-old male patient. Microscopic analyses based on routine staining and immunohistochemistry were used to discuss the cells found in pericoronal follicle. This paper reinforces the importance of association between clinical history and radiographic features with microscopic pericoronal follicle examination for diagnosis of this hamartomatous lesion.
