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[¹⁸F-FDG PET/CT. Its correlation with carcinoembryonic antigen in patients with colorectal carcinoma]
Oliva Granados Rangel1, Gisela Estrada1, Javier Altamirano1
1Unidad pet/ct Ciclotrón, Universidad Nacional Autónoma de México, México, D.F.
Background:
¹⁸F-FDG PET has been shown to be highly accurate for recurrent and metastatic disease as well as in restaging. The carcinoembryonic antigen (CEA) can be used as a marker of prognosis and recurrence.
Objective:
To evaluate the association between the presence of lesions detected with 18F-FDG PET/CT and CEA values in patients with colorectal carcinoma.
Material And Methods:
We reviewed the records of 2,051 patients who underwent PET/CT to identify all the patients with colorectal carcinoma and previous CEA.
Results:
We included a total of 101 patients, 51 women and 50 men, with an average age of 60.21 years. The clinical stage that prevailed was ECIIA, with moderately differentiated adenocarcinoma histology (88.12%). There was agreement between the elevation of CEA and lesions detected by PET/CT in 73.9%. From the patients with normal values of CEA, in 42% the PET/CT study was positive for tumoral recurrence or metastases.
Conclusions:
Our study revealed that 18F-FDG PET/CT can provided additional information in up to 42% of patients with normal ranges of carcinoembryonic antigen, detecting early recurrence or metastases.
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