Related Experiment Videos
Coordinate regulation and sensory transduction in the control of bacterial virulence
J F Miller1, J J Mekalanos, S Falkow
1Department of Microbiology and Immunology, Stanford University, CA 94305.
Science (New York, N.Y.)
|February 17, 1989
Abstract:
Genes and operons that encode bacterial virulence factors are often subject to coordinate regulation. These regulatory systems are capable of responding to various environmental signals that may be encountered during the infectious cycle. For some pathogens, proteins that mediate sensory transduction and virulence control are similar to components of other bacterial information processing systems. Understanding the molecular mechanisms governing global regulation of pathogenicity is essential for understanding bacterial infectious diseases.