Related Experiment Video
Updated: Apr 21, 2026

09:57
A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
Published on: December 23, 2016
9.4K
Cell-penetrating poly(disulfide)s: the dependence of activity, depolymerization kinetics and intracellular
Nicolas Chuard1, Giulio Gasparini, Aurélien Roux
1School of Chemistry and Biochemistry, University of Geneva, Geneva, Switzerland. stefan.matile@unige.ch.
Organic & Biomolecular Chemistry
|November 7, 2014
Abstract:
We report that the depolymerization kinetics of cell-penetrating poly(disulfide)s depend exclusively on their length and propose a kinetic uptake model to explain why their intracellular destination changes with the increasing length from the endosomes over the cytosol to the nucleoli.

