Related Experiment Video
Updated: Apr 21, 2026

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Published on: November 28, 2010
A case of anti-NMDAR encephalitis induced by ovarian teratoma
1Renji Hospital Shanghai Jiaotong University School of Medicine, No.1260 East Road, Shanghai Pudong New Area, Shanghai, 200127, China.
Abstract:
A young woman was received in the hospital with gradually worsening neurological symptoms consistent with encephalitis. After several cerebrospinal fluid examinations, infectious encephalitis (viral, bacterial, or linked to tuberculosis or parasites) and autoimmune encephalitis were ruled out. The possibility of autoantibody-mediated encephalitis was considered, and anti-N-methyl-D-aspartate receptor (anti-NMDAR) antibodies were detected in cerebrospinal fluid and blood, thus confirming the diagnosis of anti-NMDAR encephalitis. After initial successful treatment, the disease relapsed and the repeated ultrasound investigation revealed teratoma in the left ovary, which was not observed at initial examination. Tumor was removed by laparoscopic oophorocystectomy, and the treatment with hormones and gamma globulin was continued after the surgery. The patient's conditions were gradually improving after the treatment. Correct diagnostic and prompt treatment of anti-NMDAR encephalitis remains a serious clinical challenge due to its unspecific manifestations and varying response to treatments. This article describes the details of a recent complicated case of a patient with this condition. The information will be of interest to clinicians working with encephalitis patients.
More Related Videos
Related Concept Videos
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Teratogenicity
Arboviral Encephalitis
Oogenesis

