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Frequency and molecular types of deletional alpha-thalassemia in Egypt
A Novelletto1, M Hafez, A Di Rienzo
1Dipartimento di Biologia, Università Tor Vergata, La Romanina, Rome, Italy.
Human Genetics
|February 1, 1989
Abstract:
The frequency of deletional alpha-thalassemia in the Egyptian population was estimated at 0.08 by DNA analysis of a newborn random sample. No alpha 0 determinants were found. The most frequent alpha+ determinant was the -alpha 3.7 type I in association with the medium allele at inter-zeta HVR. The -alpha 4.2 and alpha alpha alpha anti 3.7 arrangements were found at very low frequencies.