Imperatorin is a mechanism-based inactivator of CYP2B6

Liwei Zheng1, Jiaojiao Cao1, Dan Lu1

  • 1School of Pharmacy (L.Z., J.C., D.L., L.J., Y.P.), Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education (J.Z.), Shenyang Pharmaceutical University, Shenyang, Liaoning, P. R. China; and Center for Developmental Therapeutics, Seattle Children's Research Institute, Division of Gastroenterology and Hepatology, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington (J.Z.).

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