Related Experiment Video
Updated: Apr 21, 2026
11:02
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
21.9K
Small bowel intussusception due to metastatic bladder carcinoma
Seema Singh1, Rakesh Ranjan1, Naveen Sharma1
1Department of Surgery, University College of Medical Sciences and GTB Hospital, New Delhi, India.
Summary
Urinary bladder cancer rarely spreads to the small bowel, and even more rarely causes intussusception. This case highlights an extremely uncommon presentation of bladder cancer metastasis.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Urinary bladder carcinoma commonly metastasizes to lymph nodes, bone, lung, liver, and peritoneum.
- Metastasis to the small bowel from bladder cancer is exceptionally rare.
- Small bowel metastasis is more frequently associated with breast, lung, or melanoma primaries.
Observation:
- A case of adult small bowel intussusception was observed.
- The intussusception was found to be caused by metastasis from a urinary bladder carcinoma.
- This represents an extremely rare clinical presentation.
Findings:
- Confirmed metastasis from urinary bladder carcinoma as the cause of small bowel intussusception.
- Documented a rare instance of gastrointestinal metastasis from a genitourinary malignancy.
- Highlighted the unusual etiology of intussusception in this patient.
Implications:
- This case underscores the importance of considering unusual metastatic pathways for urinary bladder carcinoma.
- It expands the differential diagnosis for small bowel intussusception in adults.
- Further emphasizes the diverse and sometimes unexpected behavior of advanced cancer metastasis.
Related Concept Videos
01:29Intestinal Obstruction I: Introduction
20
Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
20
01:07Intestinal Obstruction II: Pathophysiology
25
Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
25
01:21Inflammatory Bowel Disease V: Surgical Management
913
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
913
01:30Inflammatory Bowel Disease II: Crohn's Disease
1.6K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.6K
01:19Appendicitis
17
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
17
01:25Assessment of the Rectum and Anus
2.0K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
2.0K