Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

1.1K
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
1.1K
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

1.3K
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
1.3K
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

1.1K
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
1.1K
Stereotype Content Model02:16

Stereotype Content Model

15.7K
The Stereotype Content Model (SCM) was first proposed by Susan Fiske and her colleagues (Fiske, Cuddy, Glick & Xu, 2002; see also Fiske, 2012 and Fiske, 2017). The SCM specifies that when someone encounters a new group, they will stereotype them based on two metrics: warmth—or that group’s perceived intent, and how likely they are to provide help or inflict harm—and competence—or their ability to carry out that objective. Depending on the warmth-competence...
15.7K
Schizophrenia01:17

Schizophrenia

1.8K
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
1.8K
Stereotypes, Prejudice, and Discrimination02:55

Stereotypes, Prejudice, and Discrimination

96.1K
Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
96.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shared and specific associations of amygdala nuclei volumes with PTSD symptom domains and childhood trauma: An ENIGMA-PGC PTSD mega-analysis.

Molecular psychiatry·2026
Same author

Reading speed, visual deficits, and cerebral white matter integrity in veterans with and without mild traumatic brain injury.

Frontiers in neuroscience·2026
Same author

Largely Typical Neural Activation During Monetary Reward Receipt in People With Psychosis-Spectrum Disorders and First-Degree Relatives.

Schizophrenia bulletin·2026
Same author

Cerebellar structure is abnormal in schizophrenia and deviates from bipolar disorder.

NeuroImage. Clinical·2026
Same author

Anxiety sensitivity and intolerance of uncertainty track distinct neurobehavioral dimensions of avoidance in anxiety-related disorders.

Molecular psychiatry·2026
Same author

White matter microstructure in relatives of people with schizophrenia or bipolar disorder: an ENIGMA meta-analysis.

Molecular psychiatry·2026

Related Experiment Video

Updated: Apr 21, 2026

Behavioral Tasks for Examining Identity Recognition In Mice
06:58

Behavioral Tasks for Examining Identity Recognition In Mice

Published on: February 7, 2025

1.4K

Discrimination within Recognition Memory in Schizophrenia.

Kathryn A McGuire1,2, Melanie M Blahnik1, Scott R Sponheim1,2

  • 1Minneapolis Veterans Affairs Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA.

Behavioral Sciences (Basel, Switzerland)
|November 8, 2014
PubMed
Summary
This summary is machine-generated.

Schizophrenia impairs episodic memory recognition discrimination. This deficit, unlike milder forms in relatives or bipolar disorder, involves poor discrimination between old and new items, impacting both verbal and nonverbal recall.

Keywords:
nonverbal memoryrecognition memoryschizophreniaverbal memory

More Related Videos

The Deese-Roediger-McDermott DRM Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory
07:26

The Deese-Roediger-McDermott DRM Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory

Published on: January 31, 2017

40.9K
Operant Procedures for Assessing Behavioral Flexibility in Rats
08:30

Operant Procedures for Assessing Behavioral Flexibility in Rats

Published on: February 15, 2015

21.8K

Related Experiment Videos

Last Updated: Apr 21, 2026

Behavioral Tasks for Examining Identity Recognition In Mice
06:58

Behavioral Tasks for Examining Identity Recognition In Mice

Published on: February 7, 2025

1.4K
The Deese-Roediger-McDermott DRM Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory
07:26

The Deese-Roediger-McDermott DRM Task: A Simple Cognitive Paradigm to Investigate False Memories in the Laboratory

Published on: January 31, 2017

40.9K
Operant Procedures for Assessing Behavioral Flexibility in Rats
08:30

Operant Procedures for Assessing Behavioral Flexibility in Rats

Published on: February 15, 2015

21.8K

Area of Science:

  • Cognitive Neuroscience
  • Psychiatry
  • Neuropsychology

Background:

  • Episodic memory deficits are prominent in schizophrenia.
  • First-degree relatives of individuals with schizophrenia often show milder memory impairments.
  • Previous research primarily focused on recognition rates, neglecting discrimination accuracy.

Purpose of the Study:

  • To investigate the specific nature of episodic memory dysfunction in schizophrenia by analyzing recognition discrimination (d').
  • To determine if recognition deficits are specific to schizophrenia or present in relatives and bipolar disorder.
  • To explore the impact of stimulus structure on recognition in different groups.

Main Methods:

  • Utilized the Recurring Figures Test (nonverbal) and California Verbal Learning Test (CVLT) (verbal).
  • Compared schizophrenia probands, their first-degree relatives, bipolar disorder probands, their relatives, and healthy controls.
  • Measured recognition discrimination (d') to assess the ability to distinguish old from new items, accounting for false recognition.

Main Results:

  • Schizophrenia patients exhibited significantly poorer recognition discrimination in both nonverbal and verbal tasks.
  • No significant recognition discrimination deficits were found in first-degree relatives of schizophrenia patients or in bipolar disorder probands.
  • Both schizophrenia and bipolar probands failed to leverage geometric structure for improved nonverbal recognition compared to controls.

Conclusions:

  • Episodic memory dysfunction in schizophrenia is characterized by impaired recognition discrimination across various domains.
  • This deficit reflects a reduced ability to utilize item content for differentiating old from new information.
  • The specific recognition discrimination impairment appears unique to schizophrenia, distinguishing it from relatives and bipolar disorder.