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Outcomes of pediatric patients undergoing cardiac catheterization while on extracorporeal membrane oxygenation
Ryan Callahan1, Sara M Trucco, Peter D Wearden
1Division of Cardiology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh Medical School, Pittsburgh, PA, USA, ryan.callahan@cardio.chboston.org.
Insights
Cardiac catheterization during extracorporeal membrane oxygenation (ECMO) is safe for pediatric patients. This procedure provides vital diagnostic information and interventions, improving survival rates for critically ill children.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Critical Care Medicine
Background:
- Extracorporeal membrane oxygenation (ECMO) is crucial for pediatric respiratory and cardiovascular failure.
- Limited recent literature exists on cardiac catheterization outcomes in pediatric ECMO patients.
Purpose of the Study:
- To explore indications for cardiac catheterization in pediatric ECMO patients.
- To review catheter interventions performed during ECMO.
- To assess the safety and survival outcomes of these procedures.
Main Methods:
- Retrospective review of pediatric patients undergoing cardiac catheterization on ECMO from 2004-2013.
- Analysis of indications, interventions, diagnostic findings, and procedural complications.
- Evaluation of short- and intermediate-term survival rates.
Main Results:
- 36 patients underwent 40 cardiac catheterizations; common indications included hemodynamic assessment and planned interventions.
- Catheter interventions (e.g., stenting, septostomy) were performed in 45% of cases.
- Survival to discharge was 72%, with 88% survival in patients undergoing interventions; 15% experienced procedural complications.
Conclusions:
- Cardiac catheterization and interventions are safe and feasible in pediatric ECMO patients.
- Diagnostic information obtained influences management and potentially improves survival.
- This procedure offers valuable insights and therapeutic options for critically ill children on ECMO.
Abstract:
The aim of the study is to explore the indications for cardiac catheterization while on extracorporeal membrane oxygenation (ECMO) and the various catheter interventions performed as well as assess the safety profile and determine the short- and intermediate-term survival. ECMO is a lifesaving intervention for pediatric patients with respiratory and/or cardiovascular failure. There is limited recent literature discussing the survival and outcomes of patients undergoing cardiac catheterization while on ECMO. A retrospective review of consecutive patients undergoing catheterization while on ECMO from 2004 to 2013 was performed. Thirty-six patients who underwent 40 cardiac catheterizations were identified. Indications for catheterization included hemodynamic/anatomic assessment of postoperative (16) and non-operative patients (7), planned catheter interventions (CI) (12), and cardiomyopathy assessment (5). CI were performed during 18 (45 %) catheterizations, including stenting of vessels/surgical shunts (9), balloon atrial septostomy (4), device closure of septal defects/vessels (3), thrombolysis of vessels (2), endomyocardial biopsy (2), and temporary pacer wire placement (1). Unexpected diagnostic information was found in 21 (52 %), and 13 patients were referred for surgical intervention. Successful decannulation was achieved in 86 % of patients. Survival to discharge was 72 % and intermediate survival was 69 % (median = 29 months). Survival was 88 % (15/17) among patients who underwent CI. There were six procedural complications (15 %); five vascular and one non-vascular. There were no complications related to patient transport. Cardiac catheterization and interventions while on ECMO are safe, with a survival to discharge of 72 %. Diagnostic information obtained from catheterization leads to management decisions which may impact survival.
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