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Cardiovascular risk in psoriatic patients detected by heart rate variability (HRV) analysis

Ilaria Proietti1, Gianfranco Raimondi, Nevena Skroza

  • 1Department of Dermatology "Daniele Innocenzi", A. Fiorini Hospital, Sapienza University of Rome, Rome, 04019, Italy.

Drug Development Research
|November 11, 2014
PubMed

Insights

Young patients with moderate psoriasis show increased sympathetic nervous system activity. This suggests psoriasis may independently increase cardiovascular risk, even without existing heart conditions.

Area of Science:

  • Cardiology
  • Dermatology
  • Autonomic Nervous System Research

Background:

  • Severe psoriasis is linked to higher cardiovascular disease rates.
  • Heart rate variability (HRV) noninvasively assesses autonomic control of heart rate.
  • Psoriasis patients often exhibit cardiovascular risks, necessitating further investigation.

Purpose of the Study:

  • To investigate cardiovascular risk in young, moderate psoriasis patients without comorbidities.
  • To analyze heart rate variability (HRV) for autonomic cardiac modulation imbalances.
  • To determine if moderate psoriasis is an independent cardiovascular risk factor.

Main Methods:

  • Utilized heart rate variability (HRV) analysis.
  • Focused on young patients with moderate cutaneous psoriasis.
  • Excluded participants with pre-existing cardiovascular comorbidities.

Main Results:

  • Data revealed a sympathetic nervous system dominance in cardiac autonomic modulation.
  • An imbalance favoring sympathetic activity was observed.
  • This sympathetic shift indicates potentially elevated cardiovascular risk.

Conclusions:

  • Moderate psoriasis may act as an independent cardiovascular risk factor.
  • Increased sympathetic activity in psoriasis patients is associated with higher cardiovascular risk.
  • Early identification and management of cardiovascular risk in psoriasis patients are crucial.

Keywords:
autonomic nervous systemcardiovascular riskheart rate variabilitypsoriasis

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