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Related Concept Videos

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To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
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Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
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Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
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Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
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In a linear calibration curve, there is a value called the calibration coefficient, denoted by 'r,' which measures the strength and the direction of association between two variables. The correlation coefficient value ranges from −1 to +1. A value of +1 indicates a perfect positive linear correlation, −1 denotes a perfect negative correlation, and 0 implies no correlation between the two variables. A positive correlation value establishes that as one variable increases, the...
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A thermometer measures body temperature. The common sites for measuring body temperature are the oral cavity, axillary region, temporal artery, and skin surface, such as the forehead, abdomen, and axilla. True core body temperature is assessed in the rectum, tympanic membrane, pulmonary artery, esophagus, and urinary bladder.
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Reliability of Repeated Measurements on Post-Burn Scars with Corneometer CM 825(®).

M Anthonissen1,2,3, D Daly4, R Peeters1

  • 1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|November 11, 2014
PubMed
Summary

The Corneometer CM825 is reliable for measuring water content in burn scars, showing high consistency between and within observers. However, strict protocols are needed for clinical trials due to day-to-day variability.

Keywords:
burn scarreliabilitystratum corneumwater contentwater holding capacity

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Area of Science:

  • Biophysics
  • Dermatology
  • Medical Instrumentation

Background:

  • Stratum corneum water content is crucial for evaluating burn scar biophysical properties.
  • Quantifying scar water content presents a significant challenge in clinical assessment.

Purpose of the Study:

  • To assess the reliability of repeated water content measurements on burn scars using the Corneometer CM825.
  • To investigate intra-observer, inter-observer, and day-by-day variability in scar hydration measurements.

Main Methods:

  • Evaluated 30 burn scars for water content using the Corneometer CM825.
  • Employed intra-class correlation coefficient (ICC) and within-subject coefficient of variation (WSCV) to analyze reliability.
  • Utilized Bland-Altman plots to assess the clinical significance of measurement differences.

Main Results:

  • Demonstrated excellent intra-observer (ICC=0.985) and inter-observer (ICC=0.984) reliability with low variability (WSCVintra=6.3%, WSCVinter=10.6%).
  • Identified that over 5% of differences may exceed the clinically acceptable limit of 4 a.u.
  • Showed good day-by-day reliability (ICC=0.849) but with higher variability (WSCV=20.5%).

Conclusions:

  • The Corneometer CM825 is an objective and sensitive tool for measuring skin hydration.
  • The instrument is suitable for clinical trials, provided a standardized protocol and potentially combined with other physiological measurements.
  • Strict adherence to standardized testing protocols is essential for reliable scar water content assessment.