Related Experiment Video
Updated: Apr 21, 2026
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Cancer-associated retinopathy with unusual retinal whitening
Joan J Lee1, Tamara R Vrabec, Vincent F Baldassano
1Department of Ophthalmology, Geisinger Medical Center, Danville, Pennsylvania.
Purpose:
To describe the clinical characteristics and results of ocular and systemic testing in an atypical case of cancer-associated retinopathy.
Methods:
This study is a retrospective case report of a female patient.
Results:
Rapidly progressive visual loss, vitritis, white, ring- and coin-shaped retinal lesions, and panretinal optical coherence tomography thinning preceded the diagnosis of poorly differentiated cervical carcinoma with neuroendocrine features consistent with small-cell carcinoma.
Conclusion:
Cancer-associated retinopathy can present with ring- and coin-shaped retinal lesions, vitritis, and panretinal thinning. The presence of intraocular inflammation and retinal and choroidal vasculopathy may herald more rapid visual demise.
Related Concept Videos
01:27Diabetic Retinopathy
01:20The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
01:20The Retinoblastoma Gene