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Updated: Apr 21, 2026

Measuring Active and Passive Tameness Separately in Mice
Published on: August 10, 2018
Behavior genetics and the domestication of animals
1IFM Biology, AVIAN Behavioural Genomics and Physiology Group, Linköping University, 58183 Linköping, Sweden;
Domestication consistently alters animal behavior, often linked to reduced fear and stress. Genetic and epigenetic studies reveal key mechanisms driving these behavioral changes across species.
Area of Science:
- Animal Behavior
- Genetics
- Evolutionary Biology
Background:
- Domestication across species leads to a common set of behavioral traits.
- Reduced fear and enhanced stress tolerance are key initial domestication traits.
- Many domestication behaviors may be correlated with reduced fear.
Purpose of the Study:
- To investigate the genetic mechanisms underlying behavioral domestication.
- To explore both top-down (phenotype to gene) and bottom-up (gene to phenotype) approaches.
- To discuss the role of epigenetic mechanisms in behavioral domestication.
Main Methods:
- Examining genetic loci associated with tameness in foxes and dogs.
- Identifying genetic loci linked to reduced aggression and increased sociality in chickens.
- Analyzing epigenetic mechanisms influencing animal behavior during domestication.
Main Results:
- Specific genetic loci identified for tameness in dogs and foxes.
- Genes correlated with reduced aggression and increased sociality in chickens.
- Evidence suggests epigenetic variants play a role in behavioral domestication.
Conclusions:
- Combined genetic and epigenetic approaches are powerful for studying behavioral domestication.
- Selection of epigenetic variants may have been crucial for domestication.
- Understanding these mechanisms provides insight into animal evolution and behavior.
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