Diarylethene based fluorescent switchable probes for the detection of amyloid-β pathology in Alzheimer's disease
Guanglei Lv1, Baiping Cui, Haichuang Lan
1Department of Chemistry & Innovation Center of Chemistry for Energy Materials, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China. yitao@fudan.edu.cn.
Abstract:
Two fluorescent switchable diarylethene derivatives which exhibit high affinity for amyloid-β aggregates with the increase of fluorescence intensity were reported. Moreover, the probes show excellent photochromic and anti-photobleaching properties both in vitro and in vivo.


