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Related Concept Videos

The Auditory Ossicles01:11

The Auditory Ossicles

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The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
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Autologous total ossicular replacement prosthesis.

M Malhotra1, S Varshney1, R Malhotra2

  • 1Department of Otorhinolaryngology,All India Institute of Medical Sciences,Rishikesh,Uttarakhand,India.

The Journal of Laryngology and Otology
|November 12, 2014
PubMed
Summary
This summary is machine-generated.

This study developed an autologous total ossicular replacement prosthesis for chronic otitis media, achieving sustainable hearing improvement in most patients. The biocompatible prosthesis offers a stable solution for hearing rehabilitation.

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Area of Science:

  • Otolaryngology
  • Biomaterials Science
  • Regenerative Medicine

Background:

  • Chronic otitis media often leads to ossicular chain discontinuity, impacting hearing.
  • Reconstruction of the ossicular chain is crucial for restoring auditory function.
  • Existing prostheses may have limitations in biocompatibility or long-term stability.

Purpose of the Study:

  • To develop and evaluate an autologous total ossicular replacement prosthesis.
  • To achieve sustainable hearing results in patients with chronic otitis media.
  • To assess the biocompatibility, stability, and imaging compatibility of the prosthesis.

Main Methods:

  • The study involved 40 patients with chronic otitis media and absent stapes superstructure/long process of the incus.
  • An autologous total ossicular replacement technique was employed for surgical repair.
  • Post-operative hearing was evaluated at 6 and 12 months using pure tone air conduction and air-bone gap measurements.

Main Results:

  • Successful hearing rehabilitation (pure tone average ≤ 30 dB) was achieved in 75% of patients.
  • An air-bone gap of ≤ 20 dB was attained in 82.5% of patients.
  • Mean air-bone gap improvement was 23.9 dB (p < 0.001), with greater improvement in tympanoplasty-only and intact canal wall groups.

Conclusions:

  • The developed autologous total ossicular replacement prosthesis is biocompatible, stable, and MRI compatible.
  • This technique provides sustainable hearing improvement for patients with chronic otitis media.
  • The prosthesis represents a significant advancement in ossicular reconstruction.