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Updated: Apr 21, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Decolonization of children after incision and drainage for MRSA abscess: a retrospective cohort study
S Maria E Finnell1, Marc B Rosenman2, John C Christenson3
1Children's Health Services Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN Division of Pediatric Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN Ryan White Center for Pediatric Infectious Disease, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN Regenstrief Institute for Healthcare, Indianapolis, IN sfinnell@iu.edu.
Background/Purpose:
Whether decolonization following incision and drainage (I&D) for methicillin-resistant Staphylococcus aureus (MRSA) abscess decreases repeat I&D and MRSA-positive cultures in children is unknown.
Materials/Methods:
Referral to the Pediatric Infectious Disease Service (PIDS) for decolonization was determined for eligible children (2003-2010), with outcomes studied over 12 months.
Results:
We identified 653 children; 54 had been seen by PIDS. In the PIDS group, no patients (0/54, 0%) had a repeat I&D. In the no PIDS group 36/599 (6%) had a repeat I&D, P = .06. Logistic regression modeling for repeat I&D showed no significant effect, odds ratio = 0.29; 95% confidence interval = 0.04-2.15; P = .23. In the PIDS group, 3 patients (3/54, 5.6%) had a repeat MRSA-positive culture. In the no PIDS group, 58/599 (9.7%) had a positive repeat culture, P = .46. Logistic regression modeling for positive culture showed no significant effect (odds ratio = 0.55; 95% confidence interval = 0.17-1.81; P = .32).
Conclusions:
We detected no statistically significant association between decolonization and repeat I&D or MRSA-positive culture.
Insights
Decolonization after incision and drainage for methicillin-resistant Staphylococcus aureus (MRSA) abscesses in children did not significantly reduce repeat procedures or MRSA-positive cultures in this study.
Area of Science:
- Pediatric Infectious Diseases
- Dermatology
- Public Health
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) abscesses are common in children.
- Incision and drainage (I&D) is a standard treatment for MRSA abscesses.
- The role of decolonization in preventing recurrence is unclear.
Purpose of the Study:
- To determine if decolonization following I&D for MRSA abscesses decreases repeat I&D and MRSA-positive cultures in children.
- To evaluate the effectiveness of Pediatric Infectious Disease Service (PIDS) referral for decolonization.
Main Methods:
- Retrospective study of children treated for MRSA abscesses between 2003-2010.
- Comparison of outcomes between children referred to PIDS for decolonization and those not referred.
- Outcomes assessed over a 12-month follow-up period included repeat I&D and MRSA-positive cultures.
Main Results:
- 54 children were seen by PIDS, and 599 were not.
- No repeat I&D occurred in the PIDS group (0%), versus 6% in the no PIDS group (P = .06).
- Repeat MRSA-positive cultures occurred in 5.6% of the PIDS group versus 9.7% in the no PIDS group (P = .46).
Conclusions:
- No statistically significant association was found between decolonization and reduced rates of repeat I&D.
- Decolonization did not significantly decrease the incidence of MRSA-positive cultures in children with abscesses.
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