Related Experiment Video
Updated: Apr 21, 2026
06:12
Plasma Polishing as a New Polishing Option to Reduce the Surface Roughness of Porous Titanium Alloy for 3D Printing
Published on: April 28, 2023
2.6K
Titanium surfaces with nanostructures influence on osteoblasts proliferation: a systematic review
Maxim Goldman1, Gintaras Juodzbalys1, Valdas Vilkinis2
1Department of Maxillofacial Surgery, Lithuanian University of Health Sciences, Kaunas Lithuania.
Journal of Oral & Maxillofacial Research
|November 12, 2014
Summary
Nanotechnology enhances titanium implant surfaces, promoting osteoblast proliferation in most studies. Further research is needed to determine the optimal nanostructure for dental implants.
Area of Science:
- Biomaterials Science
- Nanotechnology in Implantology
- Dental Implant Research
Background:
- Nanotechnology is increasingly utilized in implantology, showing promising effects.
- Titanium implants are common in dental and orthopedic applications.
- Surface modifications influence implant osseointegration and cellular response.
Purpose of the Study:
- To review and compare the effects of various nanostructure surface modifications of titanium implants on osteoblast proliferation.
- To synthesize current evidence on nanotechnology's role in enhancing implant surfaces.
Main Methods:
- A systematic literature review of English articles published between 2009-2014 was performed.
- MEDLINE database was searched using terms like "Titanium implant", "Titanium surface with nanostructure", and "Osteoblast".
- Studies included in vitro and/or in vivo evaluations of nanostructured titanium implant surfaces against control samples, focusing on osteoblast proliferation.
Main Results:
- 32 studies involving 122 sample groups were analyzed.
- Surface modifications were categorized into direct ablative (19 studies) and nanocomposite additive (13 studies).
- A majority of studies (24) reported positive effects of nanostructured surfaces on osteoblast proliferation, while 6 reported negative effects and 2 found no significant difference.
Conclusions:
- Nanostructured surfaces offer a significant advantage for titanium implants.
- Further comparative studies are necessary to identify the optimal nanostructure for implant surfaces.
