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Acitretin systemic and retinoic acid 0.1% cream supression of basal cell carcinoma
Xi-Bao Zhang1, San-Quan Zhang1, Chang-Xing Li2
1Guangzhou Institute of Dermatology, Guangzhou, China;
Abstract:
Retinoids have been used for years as monotherapy and/or in combination for treatment and suppression of cutaneous malignancies in patients with basal cell nevus syndrome, xeroderma pigmentosum, or cutaneous T-cell lymphoma (CTCL) basal cell carcinoma (BCC). We report 4 cases with BCC confirmed by histopathology who were treated by short-term systemic acitretin combined with retinoic acid 0.1% cream. The 4 cases with BCC showed good response to the treatment without severe adverse effects during treatment and follow-up. The finding suggests that acitretin may be an appropriate treatment option for elderly patients who require less invasive treatment for BCC.
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